Brian Marquardt, Ph.D.

Principal Engineer at the Applied Physics Laboratory
Affiliate Assistant Professor in Electrical Engineering
Director, Center for Process Analysis and Control

Ph.D. in Analytical Chemistry from the University of South Carolina in 1997
Founder and director of the Applied Optical Sensing Laboratory located within the Applied Physics Lab

• Scientific Advisory Board member for IFPAC (Int. Federation of Process Analytical Chemistry)
• Federation of Analytical Chemistry and Spectroscopy Society active member – Teach Short Courses, Section Head for Process Analysis, Session Leader for Process Spectroscopy and Process Raman.
• Visiting Scholar – Matforsk ( Food Research Institute of Norway)
• Instructor and advisor for FDA Process Analytical Technology (PAT) initiative and certification program for reviewers and inspectors
• Reviewer for: Talanta, Applied Spectroscopy, Analytical Chemistry, Spec. Chimica Acta
• Reviewed proposals for: NSF, NSF SBIR, CPAC, DOE
• Society for Applied Spectroscopy (1997 – Present)
• Coblentz Society (1997 - Present)

RECENT PUBLICATIONS:

• T. Dearing, W. Thompson, C. Rechsteiner and B.J. Marquardt, “Characterization of Crude Oil Products Using the Data Fusion of Process Raman, IR and NMR Spectra,” Appl. Spectrosc., 65(2), 181-186, 2011.
• E. Gunn, L. Wong, C.W. Branham, B. Marquardt and B. Kahr, “Extinction mapping of polycrystalline patterns,” CrystEngComm, 13(4), 1123-1126, 2011.
• C. Smith, C. Branham, B. Marquardt, K. Mann, “Oxygen Gas Sensing by Luminescence Queching with Crystals of Cu(xantphos)(phen)+ Complexes”, JACS, 132(40), 14079-14085, 2010.
• K.A. McGee, B.J. Marquardt and K.R. Mann, “Concurrent Sensing of Benzene and Oxygen by a Crystalline Salt of Tris(5,6-dimethyl-1,10 phenanthroline) ruthenium(II)”, Inorg. Chem., 47, 9143, 2008.
• N. K. Afseth, B.J. Marquardt, and J.P. Wold, “A Chromatographic Approach for Fluorescence Rejection in Raman Analysis,” Appl. Spectrosc, 61(12), 1283, 2007.
• K. R. Mann, J. R. Burney, K. A. McGee, B. J. Marquardt, “Crystalline Oxygen Sensors that Contain Ruthenium Complexes,” JACS, 129(49), 15092, 2007.
• B. J. Marquardt, “Application of On-Line Raman Spectroscopy to Characterize and Optimize a Continuous Microreactor,” (Eds) Koch, M.V.; VandenBussche, K.M.; and Chrisman, R.W., Micro Instrumentation for High Throughput Experimentation and Process Intensification – a Tool for PAT, Wiley-VCH, Chapter 9.2, 2007.
• B. K. Dable,  B. J. Marquardt,* ”Characterization and Quantitation o a Tertiary Mixture of Salts by Raman Spectroscopy in Simulated Hydrothermal Vent Fluid,” App. Spectrosc, 60(7), 773, 2006.
• N. K. Afseth, V.H. Segtnan, B.J. Marquardt, and J.P. Wold, “Raman and Near Infrared Spectroscopy for Quantification of Fat Composition in a Complex Food Model System,” Appl. Spectrosc, 59(11), 1324, 2005.
• B. K. Dable, K. S. Booksh, B. J. Marquardt*,” Rapid Multivariate Curve Resolution Applied to Near Real-Time Process Monitoring with HPLC/Raman Data,” Anal. Chimica Acta, 544(1-2), 71, 2005.
• A. E. Moe, S. Marx, N. Banani, M. Liu, B. Marquardt, and D. M. Wilson, “Improvements in LED-based Fluorescence Analysis Systems,” Sensors and Actuators B, 111-112, 230, 2005.
• V. Nagarajan, B. J. Marquardt, “Spectroscopic Imaging of Protein Crystals in Crystallization Drops,” J. of Func. And Struct. Genomics, 6(23), 203, 2005.